Publications Research group Krüger

1. Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer.
Grünwald B, Vandooren J, Locatelli E, Fiten P, Opdenakker G, Proost P, Krüger A, Lellouche JP, Israel LL, Shenkman L, Comes Franchini M
J Control Release. 2016 Oct 10.
PMID: 27545397 [PubMed - in process]
2. Pancreatic Pre-malignant Lesions Secrete TIMP1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Pre-Metastatic Niche in the Liver.
Grünwald B, Harant V, Schaten S, Frühschütz M, Spallek R, Höchst B, Stutzer K, Berchtold S, Erkan M, Prokopchuk O, Martignoni M, Esposito I, Heikenwalder M, Gupta A, Siveke J, Saftig P, Knolle P, Wohlleber D, Krüger A
Gastroenterology. 2016 Aug 6.
PMID: 27506299 [PubMed - as supplied by publisher]
3. Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow.
Grunwald B, Vandooren J, Gerg M, Ahomaa K, Hunger A, Berchtold S, Akbareian S, Schaten S, Knolle P, Edwards DR, Opdenakker G, Kruger A
Mol Cancer Res. 2016 Aug 3.
PMID: 27489361 [PubMed - as supplied by publisher]
4. The induction of human myeloid derived suppressor cells through hepatic stellate cells is dose-dependently inhibited by the tyrosine kinase inhibitors nilotinib, dasatinib and sorafenib, but not sunitinib.
Heine A, Schilling J, Grünwald B, Krüger A, Gevensleben H, Held SA, Garbi N, Kurts C, Brossart P, Knolle P, Diehl L, Höchst B
Cancer Immunol Immunother. 2016 Mar .
PMID: 26786874 [PubMed - in process]
5. Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.
Beck P, Cui H, Hegemann JD, Marahiel MA, Krüger A, Groll M
ChemMedChem. 2015 Dec .
PMID: 26471124 [PubMed - in process]
6. Premetastatic niche formation in the liver: emerging mechanisms and mouse models.
Krüger A
J Mol Med (Berl). 2015 Nov .
PMID: 26400831 [PubMed - in process]
7. TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice.
Kobuch J, Cui H, Grünwald B, Saftig P, Knolle PA, Krüger A
Haematologica. 2015 Aug .
PMID: 26001794 [PubMed - in process]
8. Molecular targets and pathways involved in liver metastasis of colorectal cancer.
Weidle UH, Birzele F, Krüger A
Clin Exp Metastasis. 2015 Aug .
PMID: 26104118 [PubMed - in process]
9. Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Kelwick R, Wagstaff L, Decock J, Roghi C, Cooley LS, Robinson SD, Arnold H, Gavrilović J, Jaworski DM, Yamamoto K, Nagase H, Seubert B, Krüger A, Edwards DR
Int J Cancer. 2015 Feb 15.
PMID: 25099234 [PubMed - in process]
10. Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma.
Berchtold S, Grünwald B, Krüger A, Reithmeier A, Hähl T, Cheng T, Feuchtinger A, Born D, Erkan M, Kleeff J, Esposito I
Cancer Lett. 2015 Jan 28.
PMID: 25449434 [PubMed - in process]