Publications Research group Knolle

Gastroenterology. 1996 Apr .

Antigen-presenting function and B7 expression of murine sinusoidal endothelial cells and Kupffer cells.

Lohse AW, Knolle PA, Bilo K, Uhrig A, Waldmann C, Ibe M, Schmitt E, Gerken G, Meyer Zum Büschenfelde KH

Inflammatory liver disease as well as rejection of liver allografts are thought to be mediated by resident antigen-presenting cells in the liver. At the same time, in vivo antigen presentation in the liver appears to be a more tolerogenic than systemic antigen challenge. The aim of this study was to show and characterize the antigen-presenting capability of sinusoidal endothelial cells and Kupffer cells.

PMID: 8613007 [PubMed - in process]