2018
1. Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes.
Manske K, Kallin N, König V, Schneider A, Kurz S, Bosch M, Welz M, Cheng RL, Bengsch B, Steiger K, Protzer U, Thimme R, Knolle PA, Wohlleber D
Hepatology. 2018 May 05.
PMID:
29729204 [PubMed - as supplied by publisher]
2. Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis.
Welz M, Eickhoff S, Abdullah Z, Trebicka J, Gartlan KH, Spicer JA, Demetris AJ, Akhlaghi H, Anton M, Manske K, Zehn D, Nieswandt B, Kurts C, Trapani JA, Knolle P, Wohlleber D, Kastenmüller W
Nat Commun. 2018 Nov 15.
2017
3. Rescue of T-cell function during persistent pulmonary adenoviral infection by TLR9 activation.
Holland T, Wohlleber D, Marx S, Kreutzberg T, Vento-Asturias S, Schmitt-Mbamunyo C, Welz M, Janas M, Komander K, Eickhoff S, Brewitz A, Hasenberg M, Männ L, Gunzer M, Wilhelm C, Kastenmüller W, Knolle P, Abdullah Z, Kurts C, Garbi N
J Allergy Clin Immunol. 2017 Aug 18.
PMID:
28826775 [PubMed - as supplied by publisher]
4. Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.
Yuan D, Huang S, Berger E, Liu L, Gross N, Heinzmann F, Ringelhan M, Connor TO, Stadler M, Meister M, Weber J, Öllinger R, Simonavicius N, Reisinger F, Hartmann D, Meyer R, Reich M, Seehawer M, Leone V, Höchst B, Wohlleber D, Jörs S, Prinz M, Spalding D, Protzer U, Luedde T, Terracciano L, Matter M, Longerich T, Knolle P, Ried T, Keitel V, Geisler F, Unger K, Cinnamon E, Pikarsky E, Hüser N, Davis RJ, Tschaharganeh DF, Rad R, Weber A, Zender L, Haller D, Heikenwalder M
Cancer Cell. 2017 Jun 12.
5. Targeted antigen delivery to dendritic cells elicits robust antiviral T cell-mediated immunity in the liver.
Volckmar J, Gereke M, Ebensen T, Riese P, Philipsen L, Lienenklaus S, Wohlleber D, Klopfleisch R, Stegemann-Koniszewski S, Müller AJ, Gruber AD, Knolle P, Guzman CA, Bruder D
Sci Rep. 2017 Mar 07.
2016
6. Liver sinusoidal endothelial cell cross-priming is supported by CD4 T cell-derived IL-2.
Wittlich M, Dudek M, Böttcher JP, Schanz O, Hegenbarth S, Bopp T, Schmitt E, Kurts C, Garbers C, Rose John S, Knolle PA, Wohlleber D
J Hepatol. 2016 Dec 23.
PMID:
28025060 [PubMed - as supplied by publisher]
8. Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4.
Schuette V, Embgenbroich M, Ulas T, Welz M, Schulte-Schrepping J, Draffehn AM, Quast T, Koch K, Nehring M, König J, Zweynert A, Harms FL, Steiner N, Limmer A, Förster I, Berberich-Siebelt F, Knolle PA, Wohlleber D, Kolanus W, Beyer M, Schultze JL, Burgdorf S
Proc Natl Acad Sci U S A. 2016 Sep 20.
9. Pancreatic Pre-malignant Lesions Secrete TIMP1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Pre-Metastatic Niche in the Liver.
Grünwald B, Harant V, Schaten S, Frühschütz M, Spallek R, Höchst B, Stutzer K, Berchtold S, Erkan M, Prokopchuk O, Martignoni M, Esposito I, Heikenwalder M, Gupta A, Siveke J, Saftig P, Knolle P, Wohlleber D, Krüger A
Gastroenterology. 2016 Aug 6.
PMID:
27506299 [PubMed - as supplied by publisher]
10. Systemic Ablation of MMP9 Triggers Invasive Growth and Metastasis of Pancreatic Cancer via Deregulation of IL-6 Expression in the Bone Marrow.
Grunwald B, Vandooren J, Gerg M, Ahomaa K, Hunger A, Berchtold S, Akbareian S, Schaten S, Knolle P, Edwards DR, Opdenakker G, Kruger A
Mol Cancer Res. 2016 Aug 3.
PMID:
27489361 [PubMed - as supplied by publisher]
