J Orofac Orthop. 2012 Dec .

Osteoimmunological mechanisms involved in orthodontically and bacterially induced periodontal stress.

Konermann A, Götz W, Wohlleber D, Knolle P, Deschner J, Jäger A

Orthodontic tooth movement is known to cause sterile inflammation of the periodontal ligament (PDL). It may also be accompanied by pathological effects of external apical root resorption, with interindividual differences in the incidence and extent of resorption. An involvement of autoimmunological mechanisms is currently under discussion. This study aimed to improve our understanding of similarities between the inflammatory mechanisms underlying the pathophysiology of periodontitis and root resorption.

PMID: 23001185 [PubMed - in process]